It is recommended that a dose of 10000 to 20000 I.U. of tetanus antitoxin should be injected intramuscularly soon after admission of patient with symptoms of tetanus such as lockjaw, muscular spasms, etc. after taking precautions against possible serum reaction. The dose of 10000 to 20000 I.U. is now considered adequate (J.C.Patel et al. proceeding of the first international conference of tetanus p 346, B.J.Vakil et al ibid, p.337 the study group of tetanus, Bombay 1965). In addition, symptomatic treatment consisting of antibiotics, sedatives, anticonvulsants and muscle relaxants may be given. The patient should be actively immunized with adsorbed tetanus vaccine (Tel/Vac/PTap), at the time of discharge and advised to return after 1 or 2 months for a second dose of the adsorbed tetanus and 6 to 12 months later for the third dose. [Ingredients]Equine tetanus immunoglobulin following pepsin digestion [Pharmacological action…
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